Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615365 | 0.81 | CYP2C9 (0.49) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL14990472 | 0.81 | MAOB (0.45) | CYP2C9CYP17A1CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL498377 | 0.79 | ALDH1A1 (0.56) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL14033384 | 0.79 | CYP17A1 (0.51) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL15000370 | 0.79 | LTA4H (0.47) | FAAHSMN1; SMN2LMNA | |
| SCHEMBL2426547 | 0.79 | CYP4F2 (0.40) | CYP2C9CYP17A1CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL9418032 | 0.77 | CYP2D6 (0.46) | CYP4F2CYP4A11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22414702 | 0.77 | CYP4F2 (0.41) | CYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL25598615 | 0.77 | CA12 (0.42) | CYP2C9CYP17A1CYP2C19CYP4F2CYP4A11 | |
| SCHEMBL7202728 | 0.77 | CYP2C9 (0.50) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |