Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704208 | 0.80 | TSHR (0.33) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL5713415 | 0.80 | PPARA (0.36) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL2226926 | 0.80 | PPARA (0.56) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL17049075 | 0.80 | EPHX2 (0.47) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL27716557 | 0.78 | ALDH1A1 (0.52) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL7025446 | 0.78 | NR1H4 (0.50) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL27496275 | 0.78 | TSHR (0.57) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL13806629 | 0.78 | KEAP1 (0.48) | TSHRALDH1A1DCLRE1ADCLRE1BCYP1A2 | |
| SCHEMBL27336883 | 0.76 | KLKB1 (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL8479634 | 0.74 | CA12 (0.45) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |