Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.33 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.33 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615500 | 0.80 | KLKB1 (0.41) | PPARALCKTSHREGFRKLKB1 | |
| SCHEMBL6236449 | 0.80 | CA12 (0.47) | LCKTSHREGFRALDH1A1POLB | |
| SCHEMBL17187944 | 0.78 | KDM4E (0.42) | POLB | |
| SCHEMBL17187947 | 0.76 | GABRP (0.35) | PPARAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6410000 | 0.75 | KDM4E (0.56) | ALDH1A1POLBHSD17B10CFD | |
| SCHEMBL15344558 | 0.74 | PPARA (0.53) | PPARALCKPPARGRARBKAT8 | |
| SCHEMBL5713427 | 0.73 | HMGB1 (0.40) | TSHRSMN1; SMN2ALDH1A1FOLH1HSD17B10 | |
| SCHEMBL7675644 | 0.72 | LTB4R (0.60) | MCL1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL15344634 | 0.72 | PPARA (0.47) | PPARAPPARGRARBKAT8MCL1 | |
| SCHEMBL7025446 | 0.72 | NR1H4 (0.50) | PPARARARBKLKB1CTSBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368381-B1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL NV (NL) | 2006-05-03 | — | — | EP | disclosed |
| US-7026304-B2 | 2-alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | AKZO NOBEL N.V. (NL) | 2006-04-11 | — | — | US | disclosed |
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | MERCK SHARP & DOHME B.V. (NL) | 2004-06-03 | — | — | US | disclosed |
| EP-1368381-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | Akzo Nobel N.V. (NL) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002064635-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL N.V. (NL) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | SCN1B, SCN2B, CHRNB1 | PPARA 4691/4885LCK 3733/4885PPARG 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.