SCHEMBL2861553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864530	0.82	PGK1 (0.38)	IMPDH2IMPDH1ARPRKDCPIK3CD
	SCHEMBL2855952	0.80	IMPDH2 (0.39)	IMPDH2IMPDH1ARPGRPRKDC
	SCHEMBL4137412	0.74	ADORA2A (0.39)	ADORA2AADORA1KDRPRKDCSRC
	SCHEMBL2856284	0.72	SRC (0.35)	ADORA2AADORA1KDRPRKDCSRC
	SCHEMBL2861359	0.72	SRC (0.40)	ADORA2AADORA1KDRPRKDCSRC
	SCHEMBL4146205	0.72	ADORA2A (0.40)	ADORA2AADORA1KDRPRKDCPGGT1B
	SCHEMBL4159884	0.71	PIK3CD (0.38)	ADORA2AADORA1KDRPRKDCSRC
	SCHEMBL2858897	0.70	SRC (0.44)	ADORA2AADORA1KDRPRKDCSRC
	SCHEMBL2864250	0.69	KDM4E (0.38)	ADORA2AALDH1A1KDM4EHTTRXFP1
	SCHEMBL2858902	0.69	ADORA2A (0.38)	ADORA2AADORA1ALDH1A1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.