Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613040 | 0.79 | PIM1 (0.42) | PIM1PIM2L3MBTL1EEDHTR6 | |
| SCHEMBL28632616 | 0.76 | PIM1 (0.40) | PIM1PIM2FGFR1ALKALOX5AP | |
| SCHEMBL28632664 | 0.75 | L3MBTL1 (0.46) | L3MBTL1EEDHTR6ALK | |
| SCHEMBL28615646 | 0.69 | HTR6 (0.43) | PIM1PIM2L3MBTL1HTR6 | |
| SCHEMBL15805479 | 0.68 | PTPN11 (0.43) | PIM1PIM2L3MBTL1EEDBRD4 | |
| SCHEMBL15805350 | 0.68 | PTPN11 (0.40) | PIM1PIM2L3MBTL1EEDBRD4 | |
| SCHEMBL16023226 | 0.67 | PTPN11 (0.42) | PIM1PIM2L3MBTL1EEDBRD4 | |
| SCHEMBL15805401 | 0.67 | PTPN11 (0.44) | PIM1PIM2L3MBTL1EEDBRD4 | |
| SCHEMBL16023221 | 0.67 | PTPN11 (0.44) | PIM1PIM2L3MBTL1EEDBRD4 | |
| SCHEMBL17636888 | 0.67 | PTPN11 (0.44) | PIM1PIM2L3MBTL1EEDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336751-A | High-efficiency salt-induced kinase inhibitor and preparation method thereof | 南京谷睿生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |