Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28618689 | 0.82 | HTR6 (0.43) | HTR6ALOX5PPARGPPARDPPARA | |
| SCHEMBL3330566 | 0.79 | HTR6 (0.50) | HTR6PPARGPPARDPPARABCHE | |
| SCHEMBL28623603 | 0.75 | HTR6 (0.44) | HTR6PPARGGPR119L3MBTL1BCHE | |
| SCHEMBL28632664 | 0.75 | L3MBTL1 (0.46) | HTR6L3MBTL1 | |
| SCHEMBL28613040 | 0.70 | PIM1 (0.42) | HTR6L3MBTL1PIM1PIM2MAPT | |
| SCHEMBL3327338 | 0.69 | HTR6 (0.49) | HTR6L3MBTL1BCHELMNAMEN1 | |
| SCHEMBL9901269 | 0.69 | TYK2 (0.42) | HTR6ALOX5GPR119BCHEPIM1 | |
| SCHEMBL9901268 | 0.69 | TYK2 (0.42) | HTR6ALOX5GPR119BCHEPIM1 | |
| SCHEMBL28615536 | 0.69 | PIM1 (0.40) | HTR6L3MBTL1PIM1PIM2 | |
| SCHEMBL17736163 | 0.69 | GPR119 (0.53) | TP53GPR119LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336751-A | High-efficiency salt-induced kinase inhibitor and preparation method thereof | 南京谷睿生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |