Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011090 | 0.91 | GSK3B (0.71) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL455366 | 0.84 | GSK3B (1.00) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL27855638 | 0.83 | RAB9A (1.00) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL29011091 | 0.83 | RAB9A (0.88) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28614995 | 0.82 | GSK3B (0.66) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL30386804 | 0.82 | GSK3B (0.66) | GSK3BRAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL11674120 | 0.79 | SMN1; SMN2 (0.89) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL11840510 | 0.78 | NPC1 (0.93) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL12377801 | 0.78 | SMN1; SMN2 (0.59) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL12377800 | 0.78 | KDM4E (0.68) | RAB9ANPC1SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307780-B | Preparation method of 2-amino-1, 3, 4-oxadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113307780-A | Preparation method of 2-amino-1, 3, 4-oxadiazole compound and compound prepared by same | 重庆医科大学 | 2021-08-27 | — | — | CN | disclosed |