Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614995 | 1.00 | GSK3B (0.66) | GSK3BKDM4EPDCD1CD274SMN1; SMN2 | |
| SCHEMBL29011092 | 0.85 | GSK3B (0.86) | GSK3BKDM4EPDCD1CD274SMN1; SMN2 | |
| SCHEMBL17377357 | 0.85 | GSK3B (0.86) | GSK3BKDM4EPDCD1CD274SMN1; SMN2 | |
| SCHEMBL3250240 | 0.82 | NPC1 (0.72) | KDM4ESMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL28615565 | 0.82 | GSK3B (0.71) | GSK3BKDM4EPDCD1CD274SMN1; SMN2 | |
| SCHEMBL28613942 | 0.81 | ACHE (0.70) | GSK3BKDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL30386372 | 0.81 | ACHE (0.70) | GSK3BKDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL455366 | 0.81 | GSK3B (1.00) | GSK3BKDM4ESMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1181062 | 0.81 | KDM4E (0.78) | KDM4ESMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL5477528 | 0.77 | VCP (0.80) | MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307780-B | Preparation method of 2-amino-1, 3, 4-oxadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |