Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402738 | 1.00 | CA1 (0.61) | CA1CA2ACHEATMPOLB | |
| SCHEMBL21959864 | 0.89 | MMP9 (0.54) | CA1CA2ACHEATMALDH1A1 | |
| SCHEMBL6768253 | 0.82 | POLB (0.50) | CA1CA2ACHEPOLBKMT2A | |
| SCHEMBL14445760 | 0.82 | POLB (0.54) | CA1CA2ACHEPOLBKMT2A | |
| SCHEMBL7414382 | 0.82 | CA1 (0.70) | CA1CA2ACHEATMCNR2 | |
| SCHEMBL19402736 | 0.79 | FAAH (0.49) | CA1CA2ACHEPOLBKMT2A | |
| SCHEMBL10832272 | 0.79 | ALDH1A1 (0.56) | ATMKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL13749512 | 0.79 | POLB (0.57) | CA1CA2ACHEPOLBCNR2 | |
| SCHEMBL158656 | 0.79 | POLB (0.57) | CA1CA2ACHEPOLBCNR2 | |
| SCHEMBL11453114 | 0.79 | ALDH1A1 (0.56) | CA1CA2ACHEATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071429-B | Prophyridine sulfonamide compounds and methods of use thereof | 正大天晴药业集团股份有限公司 | 2021-04-02 | — | — | CN | disclosed |