SCHEMBL2861587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2866826	0.85	DYRK1A (0.52)	KDRDYRK1AWNT1LRRK2GSK3B
	SCHEMBL2864594	0.85	KDR (0.47)	KDRDYRK1ALRRK2NPC1RAB9A
	SCHEMBL2857443	0.82	CA12 (0.46)	KDRMAPK8
	SCHEMBL2867207	0.82	KDR (0.48)	KDRDYRK1AWNT1GSK3BKCNH2
	SCHEMBL4327031	0.82	MTNR1A (0.41)	KDRDYRK1AWNT1NPC1RAB9A
	SCHEMBL2864933	0.81	PIP5K1C (0.48)	KDRDYRK1AWNT1LRRK2GSK3B
	SCHEMBL2857326	0.81	PIP5K1C (0.48)	KDRDYRK1AWNT1MAPK8CHEK1
	SCHEMBL2867525	0.81	ALPL (0.50)	KDR
	Cyclopropanecarboxylic Acid Amide SCHEMBL2861585	0.80	NPC1 (0.40)	KDRLRRK2GSK3BNPC1RAB9A
	SCHEMBL4339304	0.79	SCN9A (0.39)	KDRDYRK1AWNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.