Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | FRK | P42685 | 2/20 | 0.34 |
| ▸ | BLK | P51451 | 2/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664515 | 0.77 | FYN (0.41) | GPR119HCKSRCFRKBLK | |
| SCHEMBL21267364 | 0.73 | CDK4 (0.40) | L3MBTL3 | |
| SCHEMBL28611481 | 0.72 | L3MBTL3 (0.42) | L3MBTL3 | |
| SCHEMBL16892009 | 0.70 | PTPN11 (0.42) | L3MBTL3LCK | |
| SCHEMBL19066144 | 0.70 | L3MBTL3 (0.35) | L3MBTL3 | |
| SCHEMBL20311336 | 0.68 | ACVR1 (0.42) | L3MBTL3 | |
| SCHEMBL28484682 | 0.68 | KMT2A (0.37) | GPR119 | |
| SCHEMBL30700827 | 0.68 | AAK1 (0.43) | GPR119PDE10A | |
| SCHEMBL20037702 | 0.68 | AAK1 (0.43) | GPR119PDE10A | |
| SCHEMBL10118830 | 0.67 | MCHR1 (0.49) | GPR119HCKSRCFRKBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549069-A | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-108779117-B | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-08-31 | — | — | CN | disclosed |