Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911015 | 0.80 | KMT2A (0.43) | KMT2ALMNAGPR119LTA4HMEN1 | |
| SCHEMBL5868225 | 0.74 | LMNA (0.40) | KMT2ALMNAALDH1A1 | |
| SCHEMBL594359 | 0.73 | L3MBTL1 (0.45) | KMT2ALMNALTA4HSLC7A5MAPT | |
| SCHEMBL305032 | 0.73 | L3MBTL1 (0.45) | KMT2ALMNALTA4HSLC7A5MAPT | |
| SCHEMBL30065221 | 0.73 | L3MBTL1 (0.45) | KMT2ALMNALTA4HSLC7A5MAPT | |
| SCHEMBL5966871 | 0.72 | RAB9A (0.43) | LMNAGPR119POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL595486 | 0.71 | ATM (0.44) | KMT2ALMNALTA4HSLC7A5MAPT | |
| Hydrochloric Acid SCHEMBL628345 | 0.71 | ATM (0.44) | KMT2ALMNALTA4HSLC7A5MAPT | |
| Hydrochloric Acid SCHEMBL304679 | 0.71 | ATM (0.44) | KMT2ALMNALTA4HSLC7A5MAPT | |
| SCHEMBL2177879 | 0.70 | P2RX7 (0.37) | LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107446015-B | Coumarin derivative and preparation method and application thereof | 首都医科大学 | 2020-10-16 | — | — | CN | disclosed |