Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066144 | 0.81 | L3MBTL3 (0.35) | L3MBTL3EGFRALKPDE1BMCHR1 | |
| SCHEMBL16892009 | 0.76 | PTPN11 (0.42) | L3MBTL3PDE1BHRH3PTPN11ACVR1 | |
| SCHEMBL20311336 | 0.75 | ACVR1 (0.42) | L3MBTL3EGFRPDE1BPTPN11ACVR1 | |
| SCHEMBL28535183 | 0.73 | LGMN (0.43) | L3MBTL3EGFRALKL3MBTL1PLK1 | |
| SCHEMBL1992323 | 0.73 | CDK2 (0.43) | EGFRPTPN11ACVR1CDK1CDK4 | |
| SCHEMBL28537166 | 0.72 | L3MBTL3 (0.36) | L3MBTL3EGFRALKIKBKBL3MBTL1 | |
| SCHEMBL28616219 | 0.72 | GPR119 (0.36) | L3MBTL3 | |
| SCHEMBL28664515 | 0.71 | FYN (0.41) | EGFRALKMCHR1PLK1CDK4 | |
| SCHEMBL25085650 | 0.71 | ACVR1 (0.38) | L3MBTL3EGFRPDE1BHRH3PTPN11 | |
| SCHEMBL21267364 | 0.71 | CDK4 (0.40) | L3MBTL3PDE1BPTPN11ACVR1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549069-A | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-108779117-B | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-08-31 | — | — | CN | disclosed |