Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091526 | 0.80 | ACHE (0.59) | MAPTKDM4ECYP3A4ALDH1A1ALOX15 | |
| SCHEMBL19034740 | 0.80 | ACHE (0.59) | MAPTKDM4ECYP3A4ALDH1A1HPGD | |
| SCHEMBL17655758 | 0.79 | ACHE (0.76) | MAPTCYP3A4ALDH1A1ACHEKMT2A | |
| SCHEMBL24740979 | 0.77 | MAPT (0.52) | MAPTKDM4ECYP3A4ALDH1A1TP53 | |
| SCHEMBL11406884 | 0.76 | MAOB (0.50) | MAPTCYP3A4ACHEPOLBKMT2A | |
| SCHEMBL16541244 | 0.76 | SELL (0.52) | MAPTKDM4ECYP3A4ALDH1A1TP53 | |
| SCHEMBL30237826 | 0.74 | ALDH1A1 (0.69) | MAPTKDM4ECYP3A4ALDH1A1TP53 | |
| SCHEMBL24715481 | 0.74 | ERN1 (0.44) | MAPTKDM4ECYP3A4ALDH1A1TP53 | |
| SCHEMBL18550567 | 0.73 | MAPT (0.47) | MAPTKDM4ECYP3A4ALDH1A1TP53 | |
| SCHEMBL29421895 | 0.72 | ACHE (0.70) | MAPTKDM4ECYP3A4ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109276563-B | Application of pharmaceutical composition in preparing medicine for treating or preventing individual infection virus | 珠海市鑫展生物科技有限公司 | 2021-04-09 | — | — | CN | disclosed |