SCHEMBL24740979

SCHEMBL24740979

COc1cccc(-c2cc(C)cc(OC)c2O)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
MAPK1 P28482 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PKM P14618 1/20 0.46
ERN1 O75460 4/20 0.46
RXRA P19793 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TLR2 O60603 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18550567 0.91 MAPT (0.47) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL24715481 0.90 ERN1 (0.44) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL7520392 0.87 ERN1 (0.57) MAPTKDM4EALDH1A1LMNAPKM
SCHEMBL8004728 0.84 KDM4E (0.70) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL18523530 0.80 ACHE (0.50) MAPTKDM4EALDH1A1CYP3A4ERN1
SCHEMBL890499 0.80 ACHE (0.55) MAPTKDM4EALDH1A1LMNACYP3A4
SCHEMBL16024748 0.79 ERN1 (0.50) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL17265426 0.79 ERN1 (0.44) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL31536724 0.79 ALDH1A1 (0.61) MAPTKDM4EALDH1A1LMNATP53
SCHEMBL16014627 0.79 ACHE (0.48) MAPTALDH1A1LMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11519011-B2 Conversion of lignin into bioplastics and lipid fuels THE TEXAS A&M UNIVERSITY SYSTEM (US) 2022-12-06 US disclosed