Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624694 | 0.88 | SRC (0.48) | RIPK2SRCABL1PIK3CDEGFR | |
| SCHEMBL28631641 | 0.85 | CYP1A1 (0.43) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL28624086 | 0.82 | SRC (0.53) | SRCKDRHPGDSMN1; SMN2CYP1A1 | |
| SCHEMBL28616734 | 0.82 | SRC (0.48) | RIPK2SRCABL1PIK3CDEGFR | |
| SCHEMBL28922043 | 0.82 | PAX8 (0.45) | RIPK2SRCABL1PIK3CDEGFR | |
| SCHEMBL28614006 | 0.79 | BRAF (0.54) | RIPK2SRCEGFRKDRSMN1; SMN2 | |
| SCHEMBL28624707 | 0.75 | RIPK2 (0.46) | RIPK2SRCABL1PIK3CDEGFR | |
| SCHEMBL28616410 | 0.75 | RIPK2 (0.40) | RIPK2SRCABL1PIK3CDEGFR | |
| SCHEMBL28612774 | 0.73 | TUBB4A (0.49) | SRCKDRHPGDSMN1; SMN2TUBB4A | |
| SCHEMBL8310316 | 0.72 | ADORA2A (0.51) | RIPK2SRCABL1PIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-B | Microtubule inhibitors, methods of preparation and uses thereof | 成都威斯克生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |