Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631644 | 0.86 | CHEK1 (0.38) | SRCABL1TUBB4ATUBBTUBA3C | |
| SCHEMBL28624088 | 0.83 | PTGS2 (0.44) | HPGDSMN1; SMN2SRCTUBB4ATUBB | |
| SCHEMBL28614008 | 0.81 | BRAF (0.47) | SMN1; SMN2SRCTUBB4ATUBBTUBA3C | |
| SCHEMBL28624694 | 0.78 | SRC (0.48) | RIPK2HPGDSMN1; SMN2SRCABL1 | |
| SCHEMBL28616407 | 0.75 | RIPK2 (0.44) | RIPK2HPGDSMN1; SMN2SRCABL1 | |
| SCHEMBL28922043 | 0.75 | PAX8 (0.45) | RIPK2SMN1; SMN2SRCABL1TUBB4A | |
| SCHEMBL28616734 | 0.73 | SRC (0.48) | RIPK2SRCABL1TUBB4ATUBB | |
| SCHEMBL28624707 | 0.73 | RIPK2 (0.46) | RIPK2SRCABL1TUBB4ATUBB | |
| SCHEMBL8310316 | 0.70 | ADORA2A (0.51) | RIPK2HPGDSRCABL1TUBB4A | |
| SCHEMBL8355956 | 0.69 | RIPK2 (0.71) | RIPK2SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409663-B | Microtubule inhibitors, methods of preparation and uses thereof | 成都威斯克生物医药有限公司 | 2021-09-03 | — | — | CN | disclosed |