Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 1.00 |
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL27414690 | 0.88 | CREBBP (0.78) | CREBBPCNR1NR2F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28623979 | 0.86 | LMNA (0.76) | CREBBPNR2F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8959817 | 0.82 | CNR1 (0.72) | CREBBPCNR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2554994 | 0.82 | CREBBP (1.00) | CREBBPNR2F2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8959942 | 0.81 | CNR1 (0.71) | CREBBPCNR1ALDH1A1LMNAPOLB | |
| SCHEMBL1250185 | 0.81 | ALDH1A1 (0.77) | CREBBPCNR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28840703 | 0.80 | CNR1 (0.69) | CREBBPCNR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8792799 | 0.80 | CREBBP (0.65) | CREBBPCNR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16104243 | 0.79 | CNR2 (0.74) | CREBBPCNR1CNR2 | |
| SCHEMBL17176279 | 0.79 | CREBBP (0.73) | CREBBPNR2F2ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |