Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616563 | 0.86 | CREBBP (1.00) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL8528645 | 0.84 | ALDH1A1 (0.71) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL18572850 | 0.84 | LMNA (0.55) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL13490809 | 0.83 | ALDH1A1 (0.69) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL19208616 | 0.83 | LMNA (0.54) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL17023509 | 0.82 | GAA (0.58) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL8528642 | 0.82 | ALDH1A1 (0.67) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL14880155 | 0.82 | ALDH1A1 (0.67) | LMNACREBBPL3MBTL1POLBALDH1A1 | |
| SCHEMBL12479832 | 0.81 | KMT2A (0.73) | LMNACREBBPL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL29781911 | 0.81 | KMT2A (0.73) | LMNACREBBPL3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |