Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026196 | 1.00 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL29385092 | 1.00 | RAPGEF4 (0.31) | RAPGEF4 | |
| SCHEMBL6026676 | 0.82 | — | — | |
| SCHEMBL11116745 | 0.80 | HSP90AA1 (0.32) | — | |
| SCHEMBL20128346 | 0.75 | — | — | |
| SCHEMBL191365 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL2085147 | 0.75 | — | — | |
| SCHEMBL2110353 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL2112663 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL191997 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114184699-B | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-114184699-A | Method for determining potential genotoxic impurities in esomeprazole sodium by liquid chromatography-mass spectrometry | 北京悦康科创医药科技股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-112645873-A | Synthetic method of 4-methoxy-2, 3, 5-trimethyl-pyridine nitrogen oxide | 荆楚理工学院 | 2021-04-13 | — | — | CN | claimed |
| CN-111943883-A | Production process of Orimei chloride | 抚州三和医药化工有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-109836380-A | A kind of preparation method of 4- nitro -2,3,5- trimethylpyridine-N- oxide | 盘锦研峰科技有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-102942523-A | Preparation method of omeprazole intermediate 2,3,5-trimethylpyridyl-N-oxide | Shouguang fukang pharmaceutical co ltd | 2013-02-27 | — | — | CN | claimed |
| CN-101397293-B | Green nitration method based on ion liquid catalysis | ZHEJIANG HUAYI MELANGE MEDICINE CO LTD | 2012-08-22 | — | — | CN | claimed |
| CN-101417910-B | Green nitration method of prazoles intermediate | ZHEJIANG HUAYI PHARMACEUTICAL CO LTD | 2011-07-20 | — | — | CN | claimed |
| CN-117865882-A | Preparation method of 4-nitropyridine-N-oxide | 滁州学院 | 2024-04-12 | — | — | CN | disclosed |
| CN-110317164-B | Preparation method of omeprazole intermediate | 抚州三和医药化工有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114044752-A | Production method of omeprazole drug intermediate 2-chloromethyl-3, 5-dimethyl-4-methoxypyridine hydrochloride | 上海卓鼎生物技术有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-112645873-A | Synthetic method of 4-methoxy-2, 3, 5-trimethyl-pyridine nitrogen oxide | 荆楚理工学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-112645873-A | Synthetic method of 4-methoxy-2, 3, 5-trimethyl-pyridine nitrogen oxide | 荆楚理工学院 | 2021-04-13 | — | — | CN | disclosed |
| US-4620008-A | Processes for the preparation of omeprazole and intermediates therefore | AKTIEBOLAGET HASSLE (SE) | 1986-10-28 | — | — | US | disclosed |
| US-4560693-A | ANTISECRETORY, ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-12-24 | — | — | US | disclosed |
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4544750-A | Certain pyridyl-N-oxide intermediates for the preparation of omeprazole | AKTIEBOLAGET HASSLE (SE) | 1985-10-01 | — | — | US | disclosed |
| US-4472409-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-09-18 | — | — | US | disclosed |
| EP-0103553-A1 | Intermediates for the preparation of omeprazole | Aktiebolaget Hässle (SE) | 1984-03-21 | — | — | EP | disclosed |