Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30808298 | 1.00 | GPR119 (0.32) | GPR119PDE4BPDE7AMAPK1 | |
| SCHEMBL28613438 | 0.85 | — | — | |
| SCHEMBL15751094 | 0.80 | GPR35 (0.31) | — | |
| SCHEMBL30808281 | 0.77 | PIP4K2C (0.42) | GPR119PDE4BPDE7A | |
| SCHEMBL28606328 | 0.77 | PIP4K2C (0.42) | GPR119PDE4BPDE7A | |
| SCHEMBL19073526 | 0.75 | CDC7 (0.41) | — | |
| SCHEMBL28613381 | 0.73 | PDPK1 (0.49) | GPR119 | |
| SCHEMBL21823142 | 0.72 | ALDH1A1 (0.36) | PDE4BPDE7AMAPK1 | |
| SCHEMBL12505973 | 0.72 | GPR119 (0.51) | GPR119 | |
| SCHEMBL21823036 | 0.70 | MAPK1 (0.47) | GPR119MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-113039182-A | Inhibitors of YAP/TAZ-TEAD interaction and their use in cancer treatment | 伊文蒂瓦公司 | 2021-06-25 | — | — | CN | disclosed |