SCHEMBL28616923

SCHEMBL28616923

O=C1CC(c2cc(O)cc(O)c2)Oc2cc(O)cc(O)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.81
CYP19A1 P11511 7/20 0.78
CYP3A4 P08684 6/20 0.78
CYP1A1 P04798 6/20 0.78
CYP1A2 P05177 6/20 0.78
CYP1B1 Q16678 6/20 0.78
CYP2C19 P33261 4/20 0.78
HSD17B10 Q99714 4/20 0.78
CYP2C9 P11712 3/20 0.78
CA12 O43570 3/20 0.78
CA4 P22748 3/20 0.78
CA7 P43166 3/20 0.78
MEN1 O00255 2/20 0.78
KMT2A Q03164 2/20 0.78
SLCO2B1 O94956 2/20 0.78
PSMB5 P28074 2/20 0.78
DPP4 P27487 2/20 0.78
GSK3B P49841 2/20 0.78
ALOX12 P18054 1/20 0.78
ESR1 P03372 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30689832 1.00 TTR (0.81) TTRCYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL14374975 0.91 TTR (0.78) TTRCYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL29991657 0.91 TTR (0.78) TTRCYP19A1CYP3A4CYP1A1CYP1A2
SCHEMBL15544299 0.91 TTR (0.78) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL20570 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL29351357 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL17166263 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL1048136 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL20571 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2
Naringenin SCHEMBL25894738 0.88 CYP19A1 (1.00) TTRCYP19A1CYP3A4CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106943441-B Coreopsis tinctoria extract and application thereof in preparation of antidepressant drugs 浙江大学 2022-05-31 CN claimed
CN-109856264-B Method for detecting content of effective components in blumea balsamifera medicinal material 遵义医科大学 2021-09-07 CN claimed
CN-109856264-A The detection method of active constituent content in Blumea balsamifera medicinal material 遵义医学院 2019-06-07 CN claimed
CN-120053513-A Extract of aerial parts of licorice for preventing and treating prostatic hyperplasia and preparation thereof 北京灵泉药材研究所 2025-05-30 CN disclosed
CN-114957362-B Method for separating anti-inflammatory active ingredients of coreopsis tinctoria 中国科学院西北高原生物研究所 2023-11-10 CN disclosed
CN-106943441-B Coreopsis tinctoria extract and application thereof in preparation of antidepressant drugs 浙江大学 2022-05-31 CN disclosed
CN-109856264-B Method for detecting content of effective components in blumea balsamifera medicinal material 遵义医科大学 2021-09-07 CN disclosed
CN-109856264-A The detection method of active constituent content in Blumea balsamifera medicinal material 遵义医学院 2019-06-07 CN disclosed