Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | PAK4 | O96013 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129508 | 0.73 | PAK4 (0.39) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL31368732 | 0.73 | DYRK1B (0.34) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL28619610 | 0.70 | HSD17B10 (0.40) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL31368720 | 0.69 | DYRK1B (0.36) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL30965400 | 0.69 | DYRK1B (0.36) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL30615550 | 0.63 | DYRK1B (0.37) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL30924204 | 0.63 | SPR (0.46) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL6952100 | 0.63 | SPR (0.46) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL31368719 | 0.62 | DYRK1B (0.36) | DYRK1BDYRK1APAK4CHEK1AURKA | |
| SCHEMBL22686471 | 0.62 | DYRK1B (0.42) | DYRK1BDYRK1APAK4CHEK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |