Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 7/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459798 | 0.74 | HTT (0.42) | CHEK1CDK8CDK7CDK9CDK5 | |
| SCHEMBL28616936 | 0.73 | DYRK1B (0.37) | PAK4DYRK1BDYRK1ACHEK1AURKA | |
| SCHEMBL28731684 | 0.71 | ADORA3 (0.32) | CDK8CDK7CDK9CDK5ADORA3 | |
| SCHEMBL26135410 | 0.71 | GSK3A (0.40) | KDR | |
| SCHEMBL20356432 | 0.70 | ADORA3 (0.34) | CDK9ADORA3ADORA1MAPK8 | |
| SCHEMBL26136784 | 0.70 | HSD17B10 (0.40) | PAK4DYRK1BDYRK1ACHEK1AURKA | |
| SCHEMBL25966739 | 0.69 | KAT2B (0.35) | HTTMAPTADORA3ADORA1HSP90AA1 | |
| SCHEMBL21522708 | 0.69 | CCNT1 (0.35) | CDK9ADORA3ADORA1 | |
| SCHEMBL31368719 | 0.69 | DYRK1B (0.36) | PAK4DYRK1BDYRK1ACHEK1AURKA | |
| SCHEMBL26126669 | 0.68 | CDK9 (0.39) | CDK8CDK7CDK9CDK5ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504709-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-119137103-A | CDK9 inhibitors | 拜奥列司治疗有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240150322-A1 | CDK9 Inhibitors | BAERENKRAFT THERAPEUTICS, LLC | 2024-05-09 | — | — | US | disclosed |
| WO-2023196518-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196518-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150322-A1 | CDK9 Inhibitors | CDK9, CDK19, CDK1 | PAK4 971/4885DYRK1B 112/4885DYRK1A 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.