Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LIPE | Q05469 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987609 | 1.00 | LMNA (0.50) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL29848579 | 0.81 | LMNA (0.50) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL8983549 | 0.81 | SMN1; SMN2 (0.55) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL11882534 | 0.81 | LMNA (0.53) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL20552074 | 0.80 | RAB9A (0.48) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL15673119 | 0.79 | LMNA (0.52) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL30433202 | 0.78 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2L3MBTL1PLAUALDH1A1 | |
| SCHEMBL29025473 | 0.78 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2L3MBTL1PLAUALDH1A1 | |
| SCHEMBL9751094 | 0.77 | LMNA (0.46) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL9751088 | 0.77 | LMNA (0.46) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354646-B | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-113354646-A | 8-aryloxy alkoxy substituted xanthine derivative and preparation method and application thereof | 南开大学 | 2021-09-07 | — | — | CN | disclosed |