Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.40 |
| ▸ | LIPE | Q05469 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751088 | 0.87 | LMNA (0.46) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL20552074 | 0.82 | RAB9A (0.48) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL29987609 | 0.77 | LMNA (0.50) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL28617037 | 0.77 | LMNA (0.50) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL11882534 | 0.77 | LMNA (0.53) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL11000247 | 0.76 | TDP1 (0.53) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL3998742 | 0.75 | LMNA (0.52) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL15673119 | 0.75 | LMNA (0.52) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL29848579 | 0.74 | LMNA (0.50) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 | |
| SCHEMBL8983549 | 0.74 | SMN1; SMN2 (0.55) | LMNACYP2C9TSHRAPEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041609-A | Plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-08-20 | — | — | US | disclosed |