Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937037 | 0.75 | CYP1A2 (0.44) | MAPTPOLBALDH1A1PKMNPSR1 | |
| SCHEMBL20425505 | 0.74 | CYP1A2 (0.42) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL4072987 | 0.74 | CYP1A2 (0.42) | MEN1KMT2APOLBALDH1A1PKM | |
| SCHEMBL28432379 | 0.73 | CYP1A2 (0.62) | MAPTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL1935051 | 0.72 | ADRB2 (0.43) | KMT2AALDH1A1PKMNPSR1CYP1A2 | |
| SCHEMBL1936445 | 0.72 | PPARG (0.43) | PKMNPSR1CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL28617150 | 0.69 | GAA (0.46) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4129200 | 0.69 | ALDH1A1 (0.46) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL28619121 | 0.67 | GAA (0.53) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL265030 | 0.66 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311865-B | Pyrazole-oxazolidinone compound for resisting hepatitis B virus | 上海挚盟医药科技有限公司 | 2021-08-31 | — | — | CN | disclosed |