Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438962 | 0.86 | HPGD (0.57) | KDM4EALDH1A1HSD17B10MAPTPOLB | |
| SCHEMBL31087265 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL29643993 | 0.84 | L3MBTL1 (0.53) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL31087263 | 0.84 | KDR (0.53) | KDM4EALDH1A1MAPTKDRKMT2A | |
| SCHEMBL28610628 | 0.84 | L3MBTL1 (0.53) | KDM4EALDH1A1MAPTL3MBTL1NPC1 | |
| SCHEMBL5936350 | 0.80 | HTT (0.60) | KDM4EALDH1A1MAPTKDRKMT2A | |
| SCHEMBL28611795 | 0.79 | HDAC6 (0.62) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL31087264 | 0.79 | HDAC6 (0.62) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL28499436 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10MAPTKDR | |
| SCHEMBL30025270 | 0.76 | RAB9A (0.65) | KDM4EHSD17B10MAPTPOLBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278007-B | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113278007-A | Synthetic method of 2-hydroxy-indole-3-ketone compound | 延安大学 | 2021-08-20 | — | — | CN | disclosed |