Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861774 | 0.93 | GAA (0.38) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL13711754 | 0.93 | LTB4R2 (0.43) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL2853035 | 0.91 | GAA (0.37) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL2850998 | 0.91 | LTB4R2 (0.37) | GAALTB4R2TP53 | |
| SCHEMBL2861740 | 0.91 | SLC6A4 (0.34) | LTB4R2HTR5AF2F10 | |
| SCHEMBL2861742 | 0.84 | SLC6A4 (0.37) | LTB4R2HTR5AF2F10 | |
| SCHEMBL2851001 | 0.83 | LTB4R2 (0.39) | LTB4R2 | |
| SCHEMBL13711758 | 0.83 | SLC6A4 (0.41) | LTB4R2HTR5A | |
| SCHEMBL2853674 | 0.83 | LTB4R2 (0.37) | GAALTB4R2F2F10ITGB3 | |
| SCHEMBL4457062 | 0.83 | SLC6A4 (0.35) | LTB4R2HTR5AF2F10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | disclosed |