Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711754 | 0.95 | LTB4R2 (0.43) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL2853035 | 0.94 | GAA (0.37) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL2861772 | 0.93 | GAA (0.36) | GAAMAPTLTB4R2HTR5AF2 | |
| SCHEMBL2861742 | 0.92 | SLC6A4 (0.37) | LTB4R2HTR5AF2F10SLC6A4 | |
| SCHEMBL2851001 | 0.91 | LTB4R2 (0.39) | LTB4R2MEN1KMT2ALMNASLC6A4 | |
| SCHEMBL13711758 | 0.89 | SLC6A4 (0.41) | LTB4R2HTR5ASLC6A4 | |
| SCHEMBL4457062 | 0.88 | SLC6A4 (0.35) | LTB4R2HTR5AF2F10ITGB3 | |
| SCHEMBL13711662 | 0.87 | SLC6A4 (0.41) | LTB4R2HTR5ASLC6A4 | |
| SCHEMBL2855107 | 0.86 | PTPN11 (0.36) | LTB4R2HTR5ASLC6A4 | |
| SCHEMBL2861740 | 0.86 | SLC6A4 (0.34) | LTB4R2HTR5AF2F10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | disclosed |