Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617674 | 1.00 | LMNA (0.44) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL22033536 | 0.84 | GPR84 (0.40) | LMNAGPR84PRSS1FFAR1ZDHHC7 | |
| SCHEMBL22033637 | 0.84 | GPR84 (0.40) | LMNAGPR84PRSS1FFAR1ZDHHC7 | |
| SCHEMBL1114880 | 0.78 | ZDHHC7 (0.47) | LMNAMEN1KMT2AGPR84PRSS1 | |
| SCHEMBL19425457 | 0.76 | CA2 (0.43) | MEN1KMT2AGPR84PRSS1CTSG | |
| SCHEMBL11657897 | 0.75 | KDM4E (0.54) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28602876 | 0.75 | MEN1 (0.45) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28919757 | 0.75 | MEN1 (0.45) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL18595283 | 0.74 | PRSS1 (0.48) | LMNAGPR84PRSS1PRSS2PRSS3 | |
| SCHEMBL79493 | 0.74 | PRSS1 (0.48) | LMNAGPR84PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113260607-A | Modified amine lipids | 英特利亚治疗股份有限公司 | 2021-08-13 | — | — | CN | disclosed |