SCHEMBL28618015

SCHEMBL28618015

O=CN1CC(Oc2c(F)cc(F)cc2F)C1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.31
ERN1 O75460 1/20 0.31
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14469238 0.83 FPR2 (0.37)
SCHEMBL28615798 0.76 HSD11B1 (0.39)
SCHEMBL20165884 0.75 RIPK1 (0.38) RIPK1
SCHEMBL20166160 0.72 SLC6A4 (0.41)
Hydrochloric Acid SCHEMBL20165897 0.71 SLC6A4 (0.41)
SCHEMBL29277453 0.70 GRIN2B (0.46)
SCHEMBL22296715 0.70 FFAR4 (0.35) RIPK1
SCHEMBL22837283 0.68 SLC6A2 (0.50)
SCHEMBL29277460 0.68 PDE4B (0.47) TACR1RIPK1
SCHEMBL29277448 0.68 FFAR4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302183-A Cyclic ureas 圣瑞诺有限公司 2021-08-24 CN disclosed