Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 3/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.67 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413895 | 1.00 | G6PD (0.85) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL2242956 | 0.92 | G6PD (1.00) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL12355277 | 0.92 | G6PD (1.00) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL12349141 | 0.90 | G6PD (0.81) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL19875637 | 0.89 | ALDH1A1 (0.80) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL12349218 | 0.85 | ALDH1A1 (0.73) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL264278 | 0.85 | ALDH1A1 (0.73) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL264277 | 0.85 | ALDH1A1 (0.73) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL11403099 | 0.81 | ALDH1A1 (0.69) | G6PDALDH1A1MAPTALOX15TSHR | |
| SCHEMBL12416931 | 0.80 | G6PD (0.85) | G6PDALDH1A1MAPTALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214252-B | Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound | 常州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-113214252-A | Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound | 常州大学 | 2021-08-06 | — | — | CN | disclosed |