SCHEMBL28618374

SCHEMBL28618374

O=C(O)c1ccccc1-c1ncccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.61
TDP1 Q9NUW8 1/20 0.61
ALDH1A1 P00352 7/20 0.54
LMNA P02545 2/20 0.54
ALOX12 P18054 1/20 0.54
NAPRT Q6XQN6 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
HMGB1 P09429 1/20 0.52
HPGD P15428 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
L3MBTL1 Q9Y468 3/20 0.50
ALOX15 P16050 2/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9265839 0.87 KDM4E (0.74) KDM4ETDP1ALDH1A1LMNAALOX12
SCHEMBL7749390 0.84 KDM4E (0.63) KDM4ETDP1ALDH1A1LMNAALOX12
SCHEMBL30555267 0.81 KDM4E (0.59) KDM4ETDP1ALDH1A1LMNANAPRT
SCHEMBL26919304 0.81 KDM4E (0.59) KDM4ETDP1ALDH1A1LMNANAPRT
SCHEMBL28265636 0.81 KDM4E (0.59) KDM4ETDP1ALDH1A1LMNAALOX12
SCHEMBL6876755 0.81 KDM4E (0.59) KDM4ETDP1ALDH1A1LMNANAPRT
SCHEMBL16627993 0.79 RIPK1 (0.47) KDM4ETDP1ALDH1A1HPGDL3MBTL1
SCHEMBL2555756 0.78 KDM4E (0.65) KDM4ETDP1ALDH1A1LMNAALOX12
SCHEMBL3820615 0.78 KDM4E (0.65) KDM4ETDP1ALDH1A1LMNAALOX12
SCHEMBL270419 0.77 KDM4E (1.00) KDM4ETDP1ALDH1A1LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113267557-B Application of lignin as MALDI matrix in detection of small molecular substances 浙江大学 2022-11-11 CN disclosed
CN-113267557-A Application of lignin as MALDI matrix in detection of small molecular substances 浙江大学 2021-08-17 CN disclosed