Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30008028 | 0.81 | PTGER1 (0.65) | MRGPRX4MEN1KMT2APTGER1CYP2C9 | |
| SCHEMBL22442364 | 0.73 | PTGER1 (0.65) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL29784206 | 0.73 | PTGER1 (0.65) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL22480969 | 0.73 | NPC1 (0.74) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL1457712 | 0.72 | MEN1 (0.63) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL28629532 | 0.72 | PTGER1 (0.59) | MRGPRX4MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4889378 | 0.71 | PTGER1 (0.71) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL7477872 | 0.71 | MRGPRX4 (0.74) | MRGPRX4TP53NFKB1RAB9ANFKB2 | |
| SCHEMBL29179211 | 0.70 | MAP4K4 (0.58) | MRGPRX4MEN1NPC1MITFTP53 | |
| SCHEMBL1934576 | 0.70 | HPGD (0.70) | MRGPRX4MEN1NPC1MITFTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704982-B | Preparation method of eltrombopag intermediate 2-hydroxy-3- (m-carboxyphenyl) aniline | 上海天慈国际药业有限公司 | 2021-09-07 | — | — | CN | disclosed |