Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628175 | 0.77 | THRA (0.54) | MEN1KMT2APPIA | |
| SCHEMBL5099680 | 0.74 | PTGER1 (1.00) | PTGER1CYP2C9CYP3A4TBXA2R | |
| SCHEMBL30008028 | 0.73 | PTGER1 (0.65) | PTGER1CYP2C9CYP3A4MRGPRX4MEN1 | |
| SCHEMBL5157932 | 0.72 | PTGER1 (0.69) | PTGER1CYP2C9CYP3A4TBXA2RMRGPRX4 | |
| SCHEMBL28619006 | 0.72 | MRGPRX4 (0.52) | PTGER1CYP2C9MRGPRX4MEN1NPC1 | |
| SCHEMBL5933532 | 0.72 | PTGER1 (0.76) | PTGER1CYP2C9CYP3A4TBXA2RMEN1 | |
| SCHEMBL5109876 | 0.71 | PTGER1 (0.93) | PTGER1CYP2C9CYP3A4TBXA2R | |
| SCHEMBL7741613 | 0.71 | RXRA (0.51) | PTGER1CYP2C9NR1H4 | |
| SCHEMBL5096132 | 0.70 | PTGER1 (1.00) | PTGER1CYP2C9CYP3A4MRGPRX4 | |
| SCHEMBL16207603 | 0.70 | PTGER1 (0.60) | PTGER1CYP2C9CYP3A4MRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704982-B | Preparation method of eltrombopag intermediate 2-hydroxy-3- (m-carboxyphenyl) aniline | 上海天慈国际药业有限公司 | 2021-09-07 | — | — | CN | disclosed |