Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643220 | 0.83 | ALDH1A1 (0.48) | PTGER1RXRARXRBRXRG | |
| SCHEMBL3786205 | 0.82 | MAOB (0.54) | PTGER1 | |
| SCHEMBL28619006 | 0.81 | MRGPRX4 (0.52) | PTGER1CYP2C9NR4A2MRGPRX4MEN1 | |
| SCHEMBL16207603 | 0.81 | PTGER1 (0.60) | PTGER1CYP2C9NR4A2MRGPRX4NR1H4 | |
| SCHEMBL30008748 | 0.81 | PTGER1 (0.60) | PTGER1CYP2C9NR4A2MRGPRX4NR1H4 | |
| SCHEMBL1705731 | 0.80 | STIM1 (0.48) | PTGER1NR1H4RXRARXRBMEN1 | |
| SCHEMBL1638061 | 0.79 | MAOB (0.62) | PTGER1CYP2C9NR4A2MRGPRX4RXRA | |
| SCHEMBL5096132 | 0.79 | PTGER1 (1.00) | PTGER1CYP2C9MRGPRX4CYP3A4RXRA | |
| SCHEMBL1618629 | 0.79 | KMO (0.61) | PTGER1NR1H4PLA2G2ARXRARXRB | |
| SCHEMBL28948616 | 0.77 | PTGER1 (0.49) | PTGER1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | disclosed |