Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205145 | 0.87 | KMT2A (0.62) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL9202235 | 0.86 | CFTR (0.57) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL9205772 | 0.86 | MAPK8 (0.65) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL18229452 | 0.83 | CTSL (0.62) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL1395865 | 0.82 | MAPT (0.62) | MAPTMEN1KMT2ASTAT3RAB9A | |
| SCHEMBL28369557 | 0.82 | MAPT (0.58) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL18229447 | 0.81 | MAPT (0.57) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL28373046 | 0.81 | LMNA (0.68) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL28373392 | 0.81 | MAPT (0.59) | MAPK8MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL28341452 | 0.80 | MAPT (0.75) | MAPTMEN1KMT2ASTAT3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |