Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556376 | 0.87 | POLB (0.55) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL3973189 | 0.87 | POLB (0.55) | RAB9AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL13883871 | 0.82 | SIRT2 (0.54) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL31556372 | 0.81 | ROCK1 (0.49) | MEN1KMT2AMAPTKDM4EROCK1 | |
| SCHEMBL5697794 | 0.81 | ROCK1 (0.49) | MEN1KMT2AMAPTKDM4EROCK1 | |
| SCHEMBL29388244 | 0.76 | ROCK1 (0.61) | ALDH1A1MAPTKDM4EHTTHSD17B10 | |
| SCHEMBL19329708 | 0.76 | ROCK1 (0.61) | ALDH1A1MAPTKDM4EHTTHSD17B10 | |
| SCHEMBL27732339 | 0.74 | TUBB4A (0.52) | RAB9AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL31454215 | 0.74 | ALDH1A1 (0.56) | NPC1RAB9AMEN1KMT2ASLC11A2 | |
| SCHEMBL16517906 | 0.73 | ROCK2 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214252-B | Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound | 常州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-113214252-A | Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound | 常州大学 | 2021-08-06 | — | — | CN | disclosed |