Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625474 | 0.99 | WDR5 (0.66) | WDR5HPGDALDH1A1GLAKDM4E | |
| SCHEMBL28620451 | 0.99 | WDR5 (0.66) | WDR5HPGDALDH1A1GLAKDM4E | |
| SCHEMBL895573 | 0.82 | WDR5 (1.00) | WDR5HPGDALDH1A1GLAKDM4E | |
| SCHEMBL29721418 | 0.82 | WDR5 (1.00) | WDR5HPGDALDH1A1GLAKDM4E | |
| SCHEMBL2055409 | 0.79 | HPGD (0.63) | HPGDALDH1A1GLAKDM4EGAA | |
| SCHEMBL11335881 | 0.79 | HPGD (0.63) | HPGDALDH1A1GLAKDM4EGAA | |
| SCHEMBL6430908 | 0.78 | ALDH1A1 (0.68) | HPGDALDH1A1GLAKDM4EGAA | |
| SCHEMBL17907459 | 0.77 | HPGD (0.60) | HPGDALDH1A1GLAKDM4EGAA | |
| SCHEMBL25247976 | 0.76 | ALDH1A1 (0.66) | HPGDALDH1A1GLAKDM4EGAA | |
| SCHEMBL14720666 | 0.76 | ALDH1A1 (0.66) | HPGDALDH1A1GLAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200884-B | Chiral carboxylic acid compound and synthesis method and application thereof | 浙江大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113200884-A | Chiral carboxylic acid compound and synthesis method and application thereof | 浙江大学 | 2021-08-03 | — | — | CN | disclosed |