SCHEMBL895573

SCHEMBL895573

O=C(O)c1ccc2ccccc2c1-c1c(C(=O)O)ccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 1.00
LDHA P00338 1/20 0.68
NR4A1 P22736 1/20 0.63
NR4A2 P43354 1/20 0.63
NR4A3 Q92570 1/20 0.63
SOS1 Q07889 1/20 0.56
CDC25B P30305 1/20 0.55
ALDH1A1 P00352 7/20 0.50
HPGD P15428 5/20 0.50
LMNA P02545 1/20 0.50
CSNK2A2 P19784 1/20 0.50
CSNK2B P67870 1/20 0.50
CSNK2A1 P68400 1/20 0.50
KDM4E B2RXH2 3/20 0.49
GLA P06280 2/20 0.49
GAA P10253 1/20 0.49
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721418 1.00 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2240626 0.90 WDR5 (0.81) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL14225351 0.89 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL23815788 0.89 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2328581 0.89 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL9124028 0.88 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29458346 0.88 WDR5 (0.79) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL2328730 0.88 WDR5 (0.77) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL8595668 0.87 WDR5 (0.76) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29795098 0.86 WDR5 (0.74) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
CN-116063686-B Alcohol-scratch-resistant transparent nylon and preparation method thereof 万华化学集团股份有限公司 2024-06-25 CN claimed
CN-116063686-A Alcohol-scratch-resistant transparent nylon and preparation method thereof 万华化学集团股份有限公司 2023-05-05 CN claimed
EP-3801880-A1 METHOD FOR IN-SITU SYNTHESIS OF METAL ORGANIC FRAMEWORKS (MOFS), COVALENT ORGANIC FRAMEWORKS (COFS) AND ZEOLITE IMIDAZOLATE FRAMEWORKS (ZIFS), AND APPLICATIONS THEREOF Desiccant Rotors International Private Ltd. (IN) 2021-04-14 EP claimed
EP-2647641-A1 New methods for the preparation of taxanes using chiral auxiliaries Accord Healthcare Inc. (CA) 2013-10-09 EP claimed
EP-1948669-B1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES ACCORD HEALTHCARE INC (CA) 2013-07-10 EP claimed
US-8207358-B2 Methods for the preparation of taxanes using chiral auxiliaries ACCORD HEALTHCARE LTD. (CA) 2012-06-26 US claimed
US-20110065912-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES ACCORD HEALTHCARE LTD. (CA) 2011-03-17 US claimed
US-20110054191-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES ACCORD HEALTHCARE LTD. (CA) 2011-03-03 US claimed
US-20090137796-A1 METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES BIOXEL PHARMA INC. (CA) 2009-05-28 US claimed
EP-1948669-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES Bioxel Pharma Inc. (CA) 2008-07-30 EP claimed
WO-2007051306-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES BIOXEL PHARMA INC. (CA) 2007-05-10 WO claimed
US-5730954-A Preparation comprising cavitate- or clathrate-forming host/guest complexes as contrast agent SCHERING AKTIENGESELLSCHAFT (DE) 1998-03-24 US claimed
EP-0357163-B1 AGENT CONSISTING OF HODT/GUEST COMPLEXES AS CONTRASTING AGENTS PRESENTING CAVITIES OF CLATHRATES SCHERING AKTIENGESELLSCHAFT (DE) 1992-06-03 EP claimed
EP-0357163-A1 Agent consisting of hodt/guest complexes as contrasting agents presenting cavities of clathrates SCHERING AKTIENGESELLSCHAFT (DE) 1990-03-07 EP claimed
JP-6199735-A None JP disclosed
JP-1186840-A None JP disclosed
US-4098842-A AMINO-CONTAINING POLYOXYALKYLENE BASF WYANDOTTE CORPORATION (US) 1978-07-04 US disclosed
US-4052325-A LIQUID ELECTROGRAPHIC DEVELOPER COMPOSITION CONTAINING REDISPERSIBLE POLYESTER TONER AND PROCESS EASTMAN KODAK COMPANY (US) 1977-10-04 US disclosed
US-4045510-A POLYAMIDES, POLYESTERS, AND POLYURETHANES COATED WITH AN ANTISTATIC RENDERING POLYETHER BASF WYANDOTTE CORPORATION (US) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065912-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES TOP2B, TOP1, TOP2A WDR5 2260/4885LDHA 3705/4885NR4A1 3038/4885
US-20090137796-A1 METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES TOP2B, TOP1, TOP2A WDR5 1885/4885LDHA 3692/4885NR4A1 2899/4885
US-20110054191-A1 NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES TOP2B, TOP1, TOP2A WDR5 2260/4885LDHA 3705/4885NR4A1 3038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.