Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.63 |
| ▸ | TGM2 | P21980 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28617369 | 0.87 | KMT2A (0.60) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28619644 | 0.87 | KMT2A (0.60) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28630813 | 0.87 | KMT2A (0.60) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28630765 | 0.79 | RAB9A (0.62) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28620836 | 0.76 | MAPK1 (0.48) | ALDH1A1MEN1KMT2ALMNANPC1 | |
| SCHEMBL28616230 | 0.76 | NPC1 (0.52) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL21179425 | 0.75 | TGM2 (0.50) | TGM2MEN1KMT2ALMNANPC1 | |
| SCHEMBL28615912 | 0.74 | TGM2 (0.61) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28620280 | 0.74 | TGM2 (0.61) | TGM2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17327878 | 0.74 | TGM2 (0.63) | TGM2MEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438279-B | Small molecule compound for overcoming EGFR drug-resistant mutation and preparation method and application thereof | 四川大学 | 2021-08-31 | — | — | CN | disclosed |