Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454320 | 0.87 | NPC1 (0.41) | HTTDHODHACMSDRAB9ALMNA | |
| SCHEMBL3794433 | 0.74 | DHODH (0.41) | DHODHRAB9AL3MBTL1PKMMEN1 | |
| SCHEMBL7713106 | 0.74 | LMNA (0.48) | HTTDHODHRAB9ALMNANPC1 | |
| SCHEMBL28837822 | 0.73 | USP7 (0.42) | RAB9AL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL6402127 | 0.72 | LMNA (0.46) | HTTDHODHRAB9ALMNANPC1 | |
| SCHEMBL25269836 | 0.71 | ALDH1A1 (0.46) | DHODHACMSDRAB9AL3MBTL1PKM | |
| SCHEMBL31398722 | 0.71 | GCGR (0.37) | RAB9AL3MBTL1PKMMEN1KMT2A | |
| SCHEMBL28940462 | 0.70 | PTPN5 (0.38) | HTTRAB9ALMNAL3MBTL1KMT2A | |
| SCHEMBL27586211 | 0.70 | ALDH1A1 (0.52) | MEN1KMT2ASMN1; SMN2MAPK1HDAC6 | |
| SCHEMBL22993074 | 0.70 | MAPK1 (0.42) | HTTACMSDRAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029689-B | Beta-hairpin peptidomimetics as selective elastase inhibitors | 波利弗尔股份公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-105873939-B | Beta-hairpin peptidomimetics as selective elastase inhibitors | 波利弗尔股份公司 | 2021-08-27 | — | — | CN | disclosed |