Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 8/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.61 |
| ▸ | PTPN5 | P54829 | 5/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607455 | 0.86 | PKM (0.67) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL28607575 | 0.84 | PKM (0.72) | PKMMEN1KMT2APTPN2PTPN1 | |
| SCHEMBL28614348 | 0.83 | BRD4 (0.73) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL28608539 | 0.83 | PKM (0.91) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL28611821 | 0.83 | PKM (0.64) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL5124261 | 0.81 | SLC10A6 (0.61) | PKMMEN1KMT2ABRD4KDM4E | |
| SCHEMBL28920614 | 0.79 | PKM (0.62) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL28607830 | 0.78 | BRD4 (1.00) | PKMMEN1KMT2ABRD4PTPN2 | |
| SCHEMBL3086551 | 0.77 | CA12 (0.60) | PKMMEN1KMT2ABRD4KDM4E | |
| SCHEMBL8279489 | 0.77 | PKM (0.65) | PKMMEN1KMT2ABRD4PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824640-B | Coumarin compound and pharmaceutical composition, preparation method and application thereof | 浙江省医学科学院 | 2021-06-29 | — | — | CN | disclosed |