M-Xylene

M-Xylene

SCHEMBL2862054

Cc1cccc(C)c1.OB(O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.75
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
PARP1 P09874 1/20 0.46
HTR3E A5X5Y0 1/20 0.44
HTR3B O95264 1/20 0.44
HTR3A P46098 1/20 0.44
HTR3D Q70Z44 1/20 0.44
HTR3C Q8WXA8 1/20 0.44
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 2/20 0.42
NPC1 O15118 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL10427453 0.87 ACHE (0.86) ACHEALDH1A1MAPK1PARP1HTR3E
M-Xylene SCHEMBL11786968 0.87 ACHE (0.86) ACHEALDH1A1MAPK1PARP1HTR3E
M-Xylene SCHEMBL28189 0.87
M-Xylene SCHEMBL891494 0.87 ACHE (1.00) ACHEALDH1A1MAPK1PARP1HTR3E
M-Xylene SCHEMBL6397624 0.87
M-Xylene SCHEMBL28161426 0.84 ACHE (0.80) ACHEALDH1A1MAPK1PARP1HTR3E
M-Xylene SCHEMBL5179379 0.83
M-Xylene SCHEMBL78260 0.83 ACHE (0.92) ACHEALDH1A1MAPK1PARP1HTR3E
M-Xylene SCHEMBL6772614 0.83
M-Xylene SCHEMBL358508 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113511970-B Synthesis method of aryl substituted alkyne 杭州师范大学 2024-04-09 CN claimed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN claimed
CN-116332985-A Preparation method of chiral phosphoric acid compound 江苏欣诺科催化剂股份有限公司 2023-06-27 CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
CN-118302418-A Aromatic heterocyclic compound and application thereof 中国科学院上海药物研究所 2024-07-05 CN disclosed
CN-113511970-B Synthesis method of aryl substituted alkyne 杭州师范大学 2024-04-09 CN disclosed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN disclosed
CN-116332985-A Preparation method of chiral phosphoric acid compound 江苏欣诺科催化剂股份有限公司 2023-06-27 CN disclosed
CN-116102533-A Aromatic heterocyclic compound and application thereof 中国科学院上海药物研究所 2023-05-12 CN disclosed
US-7772249-B2 Imidazo[1,2-b]pyridazine compound EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-08-10 US disclosed
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
US-20090181985-A1 IMIDAZO[1,2-b]PYRIDAZINE COMPOUND EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-07-16 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-20040082781-A1 Bicyclic nitrogenous fused-ring compound EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-04-29 US disclosed
EP-1364952-A1 BICYCLIC NITROGENOUS FUSED-RING COMPOUND Eisai Co., Ltd. (JP) 2003-11-26 EP disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181985-A1 IMIDAZO[1,2-b]PYRIDAZINE COMPOUND CRHR1, CRHR2, CRH ACHE 3773/4885ALDH1A1 4011/4885MAPK1 1042/4885
US-20040082781-A1 Bicyclic nitrogenous fused-ring compound CRHR1, CRH, CRHR2 ACHE 4134/4885ALDH1A1 3803/4885MAPK1 1089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.