Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630329 | 0.90 | SLC6A5 (0.46) | ATMTDP1SLC6A5ITGB3ITGA2B | |
| SCHEMBL10076057 | 0.90 | SLC6A5 (0.40) | ATMTDP1SLC6A5ITGB3ITGA2B | |
| SCHEMBL24630326 | 0.90 | SLC6A5 (0.46) | ATMTDP1SLC6A5ITGB3ITGA2B | |
| SCHEMBL30869173 | 0.88 | ATM (0.38) | ATMTDP1SLC6A5ITGB3ITGA2B | |
| SCHEMBL29336456 | 0.88 | SLC6A5 (0.48) | SLC6A5CPB2FOLH1MEN1POLB | |
| SCHEMBL7150850 | 0.86 | CTSK (0.49) | ATMTDP1ITGB3ITGA2BMEN1 | |
| SCHEMBL1304236 | 0.86 | CTSK (0.49) | ATMTDP1ITGB3ITGA2BMEN1 | |
| SCHEMBL23608150 | 0.86 | CTSK (0.49) | ATMTDP1ITGB3ITGA2BMEN1 | |
| SCHEMBL28269427 | 0.86 | CPB2 (0.42) | ATMTDP1ITGB3ITGA2BCPB2 | |
| SCHEMBL19471832 | 0.85 | GNPAT (0.39) | ATMTDP1ITGB3ITGA2BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-A | Complexes comprising ligands, spacers, peptide linkers and biomolecules | 安斯泰来制药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-113271973-A | Complex comprising a ligand and a CEACAM5 antibody Fab fragment | 安斯泰来制药株式会社 | 2021-08-17 | — | — | CN | disclosed |