Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464071 | 0.90 | PPARA (0.39) | CSNK1DMAP4K4PPARADCLRE1BMAPT | |
| SCHEMBL28620031 | 0.89 | DCLRE1B (0.43) | CSNK1DMAP4K4PPARADCLRE1BMAPT | |
| SCHEMBL19464050 | 0.86 | MAPT (0.49) | CSNK1DMAPTKMT2AMEN1HPGD | |
| SCHEMBL28618955 | 0.84 | AKR1C3 (0.37) | CSNK1DMAPTKMT2AMEN1HPGD | |
| SCHEMBL28624802 | 0.83 | KMT2A (0.37) | CSNK1DMAP4K4PPARADCLRE1BMAPT | |
| SCHEMBL20768115 | 0.77 | MAPT (0.50) | CSNK1DMAPTKMT2AMEN1HPGD | |
| SCHEMBL20768139 | 0.77 | KDM4E (0.39) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28629447 | 0.77 | DHODH (0.38) | CSNK1DMAPTKMT2AMEN1HPGD | |
| SCHEMBL20768147 | 0.76 | MAPT (0.56) | CSNK1DMAPTKMT2AMEN1HPGD | |
| SCHEMBL20782378 | 0.73 | MAPT (0.44) | MAPTHPGDKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |