Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 5/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623585 | 0.89 | DHODH (0.38) | DHODHBRS3ALDH1A1KDM4EHPGD | |
| SCHEMBL19463318 | 0.88 | DHODH (0.37) | DHODHBRS3ALDH1A1KDM4EHPGD | |
| SCHEMBL28615710 | 0.83 | BRS3 (0.35) | DHODHBRS3ALDH1A1KDM4EHPGD | |
| SCHEMBL24455511 | 0.80 | MAPT (0.42) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28618955 | 0.80 | AKR1C3 (0.37) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28621763 | 0.77 | CSNK1D (0.39) | DHODHALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19463668 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CSNK1D | |
| SCHEMBL20768145 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10CSNK1D | |
| SCHEMBL30439174 | 0.72 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10CSNK1D | |
| SCHEMBL20782378 | 0.71 | MAPT (0.44) | ALDH1A1KDM4EHPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |