Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623625 | 0.87 | MAPT (0.34) | KMT2AMAPTMEN1HPGDNPC1 | |
| SCHEMBL19464071 | 0.83 | PPARA (0.39) | KMT2AMAPTMEN1GAAHPGD | |
| SCHEMBL28620031 | 0.83 | DCLRE1B (0.43) | KMT2AMAPTMEN1GAAHPGD | |
| SCHEMBL28621763 | 0.83 | CSNK1D (0.39) | KMT2AMAPTMEN1GAAHPGD | |
| SCHEMBL28615710 | 0.81 | BRS3 (0.35) | KMT2AMAPTMEN1HPGDNPC1 | |
| SCHEMBL20768115 | 0.71 | MAPT (0.50) | KMT2AMAPTMEN1HPGDNPC1 | |
| SCHEMBL20768139 | 0.71 | KDM4E (0.39) | MAPTHPGDNPC1RAB9AKMO | |
| SCHEMBL20768147 | 0.70 | MAPT (0.56) | KMT2AMAPTMEN1HPGDNPC1 | |
| SCHEMBL19464050 | 0.70 | MAPT (0.49) | KMT2AMAPTMEN1HPGDNPC1 | |
| SCHEMBL20782378 | 0.68 | MAPT (0.44) | MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |