Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 2/20 | 0.66 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.57 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386353 | 0.94 | GSK3B (0.78) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL13171355 | 0.92 | ACHE (0.67) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL455366 | 0.88 | GSK3B (1.00) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL28615859 | 0.84 | GSK3B (0.78) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL27855638 | 0.84 | RAB9A (1.00) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL27837899 | 0.82 | GSK3B (0.81) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL28615210 | 0.80 | GSK3B (0.74) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL29011092 | 0.80 | GSK3B (0.86) | GSK3BNPC1RAB9ATP53MEN1 | |
| SCHEMBL29210254 | 0.79 | NPC1 (0.83) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL17377349 | 0.77 | GSK3B (0.78) | GSK3BNPC1RAB9ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307780-B | Preparation method of 2-amino-1, 3, 4-oxadiazole compound and compound prepared by same | 重庆医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113307780-A | Preparation method of 2-amino-1, 3, 4-oxadiazole compound and compound prepared by same | 重庆医科大学 | 2021-08-27 | — | — | CN | disclosed |